Grant-in-Aid for Scientific Research on Innovative AreasPrecise Formation of a Catalyst Having a Specified Field for Use in Extremely Difficult Substrate Conversion Reactions

Keisuke Asano » Japanese

Affiliation Graduate School of Engineering, Kyoto University
Position Assistant Professor
Contact Email
HP http://smatsubara.wixsite.com/matsubara-kyoto-u/home
Speciality organic reaction chemistry, synthetic organic chemisty, molecular catalysis chemistry
Keyword precisely designed cyclization catalysis, hydrogen bonding, organocatalysis
Institute The Chemical Society of Japan; The Society of Synthetic Organic Chemistry, Japan; The Kinki Chemical Society, Japan

Abstract

Hydrogen Bonding Networks for Precisely Designed Cyclization Catalysis

Achievement

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Original papers

  • "Desymmetrization of gem-Diols via Water-assisted Organocatalytic Enantio- and Diastereoselective Cycloetherification"
    Murata, R.; Matsumoto, A.; *Asano, K.; *Matsubara, S.
    Chem. Commun., 2020, 56, in press
  • "trans-Cyclooctenes as Chiral Ligands in Rhodium-catalyzed Asymmetric 1,4-Additions"
    Nagano, T.; Einaru, S.; Shitamichi, K.; *Asano, K.; *Matsubara, S.
    Eur. J. Org. Chem., 2020, 2020, in press
  • "Enantio- and Diastereoselective Construction of Contiguous Tetrasubstituted Chiral Carbons in Organocatalytic Oxadecalin Synthesis"
    Wada, Y.; Murata, R.; Fujii, Y.; *Asano, K.; *Matsubara, S.
    Org. Lett., 2020, 22, 4710–4715
  • "Enantioselective Bromination of Axially Chiral Cyanoarenes in the Presence of Bifunctional Organocatalysts"
    Wada, Y.; Matsumoto, A.; *Asano, K.; *Matsubara, S.
    RSC Adv., 2019, 9, 31654–31658
  • "Asymmetric syn-1,3-Dioxane Construction via Kinetic Resolution of Secondary Alcohols Using Chiral Phosphoric Acid Catalysts"
    Matsumoto, A.; *Asano, K.; *Matsubara, S.
    Asian J. Org. Chem., 2019, 8, 814–818
  • "Organocatalytic Enantio- and Diastereoselective Construction of syn-1,3-Diol Motifs via Dynamic Kinetic Resolution of In Situ Generated Chiral Cyanohydrins"
    Matsumoto, A.; *Asano, K.; *Matsubara, S.
    Org. Lett., 2019, 21, 2688–2692
  • "Asymmetric Cycloetherification of in Situ Generated Cyanohydrins through the Concomitant Construction of Three Chiral Carbon Centers"
    Kurimoto, Y.; Nasu, T.; Fujii, Y.; *Asano, K.; *Matsubara, S.
    Org. Lett., 2019, 21, 2156–2160
  • "Kinetic Resolution of Acylsilane Cyanohydrins via Organocatalytic Cycloetherification"
    Matsumoto, A.; *Asano, K.; *Matsubara, S.
    Chem.—Asian J., 2019, 14, 116–120
  • "trans-Cyclooctenes as Halolactonization Catalysts"
    Einaru, S.; Shitamichi, K.; Nagano, T.; Matsumoto, A.; *Asano, K.; *Matsubara, S.
    Angew. Chem., Int. Ed., 2018, 57, 13863–13867
  • "Asymmetric Cycloetherification by Bifunctional Organocatalyst"
    *Asano, K.; *Matsubara, S.
    Synthesis, 2018, 50, 4243–4253

Review

  • 「Catalytic Approaches to Optically Active 1,5-Benzothiazepines」 *Asano, K.; *Matsubara, S., ACS Catal., 8, 6273–6282, 2018

Conference

  • The 2nd Japanese-Sino Symposium on Catalysis for Precision Synthesis
    "Organocatalytic Enantio- and Diastereoselective Cycloetherification of Chiral Cyanohydrins", Invited Lecture
    Asano, K.
    12/6/2019~12/7/2019, Kyoto, Japan
  • 4th International Symposium on Precisely Designed Catalysts with Customized Scaffolding
    "Organocatalytic Enantio- and Diastereoselective Construction of syn-1,3-Diol Motifs via Dynamic Kinetic Resolution of In Situ Generated Chiral Cyanohydrins", Poster Presentation
    Asano, K.
    12/3/2019~12/5/2019, Nara, Japan
  • International Joint Symposium on Synthetic Organic Chemistry (12th International Symposium on Integrated Synthesis (ISONIS-11)/5th International Symposium on Middle Molecular Strategy (ISMMS-5)/2nd International Conference on Automated Flow and Microreactor Synthesis (ICAMS-2)/International Conference on Super Functional Catalysts (ICSFC))
    "Organocatalytic Enantio- and Diastereoselective Cycloetherification of Chiral Cyanohydrins", Poster Presentation
    Asano, K.; Matsubara, S.
    11/21/2019~11/23/2019, Awaji Island, Japan
  • 27th International Society of Heterocyclic Chemistry Congress (27th ISHC)
    "Organocatalytic Enantio- and Diastereoselective Construction of syn-1,3-Diol Motifs via Dynamic Kinetic Resolution of In Situ Generated Chiral Cyanohydrins", Oral Presentation
    Asano, K.
    9/1/2019~9/6/2019, Kyoto, Japan
  • The 99th CSJ Annual Meeting, Asian International Symposium - Organic and Green Chemistry -
    "Design of Organic Bases for Enantioselective Catalysis", Invited Lecture
    Asano, K.
    3/18/2019~3/18/2019, Kobe, Japan
  • The 14th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-14)
    "trans-Cyclooctenes as Halolactonization Catalysts", Oral Presentation
    Asano, K.; Einaru, S.; Shitamichi, K.; Nagano, T.; Matsumoto, A.; Matsubara, S.
    11/12/2018~11/16/2018, Kyoto, Japan

National Conference

  • 日本化学会 生産技術・製品開発ディビジョン & 京都大学 化学研究所 共催 若手講演会 2019
    "触媒活性部位の特徴を活かした有機触媒反応開発", 招待講演
    浅野 圭佑
    7/30/2019~7/30/2019, 宇治市
  • 新学術領域研究「高難度物質変換反応の開発を指向した精密制御反応場の創出」第7回公開成果報告会
    "精密環化反応場の設計に基づく四置換不斉炭素構築", 口頭発表
    浅野 圭佑
    5/16/2019~5/17/2019, 仙台市
  • 日本化学会 第99春季年会(2019)
    "有機触媒を利用した分子配座の多点認識に基づく不斉合成反応", 口頭発表
    浅野 圭佑
    3/16/2019~3/19/2019, 神戸市
  • 第11回有機触媒シンポジウム
    "トランスシクロオクテン触媒によるハロラクトン化反応", 口頭発表
    浅野 圭佑、永成 駿介、下道 謙太、長野 倫、松本 晃、松原 誠二郎
    12/3/2018~12/4/2018, 東京都・豊島区
  • 第48回複素環化学討論会
    "形式的環化付加反応による1,5-ベンゾチアゼピンの不斉ライブラリー合成", ポスター発表
    浅野 圭佑、深田 幸宏、矢尾 晃一、宮地 亮太、松原 誠二郎
    9/3/2018~9/5/2018, 長崎市

Award

  • 「第12回 井上リサーチアウォード」
    受賞者:浅野 圭佑
    贈呈元:井上科学振興財団
    受賞日:2/4/2020
  • 「Thieme Chemistry Journals Award 2020」
    受賞者:Keisuke Asano
    贈呈元:Thieme
    受賞日:1/14/2020
  • 「日本化学会 第68回進歩賞」
    受賞者:浅野 圭佑
    贈呈元:日本化学会
    受賞日:3/17/2019

Media

  • Chem.—Asian J., カバーピクチャ
    「Kinetic Resolution of Acylsilane Cyanohydrins via Organocatalytic Cycloetherification」
    Matsumoto, A.; *Asano, K.; *Matsubara, S., 12/17/2018
    PDF File

outreach

  • 小・中・高向け授業・実験・実習
    浅野 圭佑, 高津高校 京都大学研究室訪問, 京都大学 桂キャンパス
    京都市, 11/12/2018~11/12/2018