文部科学省 新学術領域研究(平成27年~31年)高難度物質変換反応の開発を指向した精密制御反応場の創出

水野 哲孝 » English

所属 東京大学大学院工学系研究科
役職 教授
連絡先 Email
HP http://park.itc.u-tokyo.ac.jp/mizuno/japanese/
専門分野 触媒化学
研究キーワード ポリオキソメタレート、担持触媒、酸化反応、分子状酸素
所属学会・研究会 日本化学会、触媒学会、石油学会、アメリカ化学会

概要

◆研究課題:
『高難度選択酸化反応のための高機能分子触媒の開発』

◆研究内容:
高度に設計した分子触媒・固体触媒を用いて、分子状酸素や過酸化水素を酸化剤とした、(1) 酸素添加反応や脱水素反応、(2) C–H、X–H(Xはヘテロ原子)結合直接活性化による脱水素クロスカップリング反応、(3)複数の反応からなるタンデム酸化反応の開発を行う。

研究業績

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原著論文

  • "CeO<sub>2</sub>-Supported Pd(II)-on-Au Nanoparticle Catalyst for Aerobic Selective α,β-Desaturation of Carbonyl Compounds Applicable to Cyclohexanones"
    Takei, D.; Yatabe, T.; Jin, X.; Yabe, T.; Mizuno, N.; Yamaguchi, K.
    ACS Catal., 2020, 10, 5057-5063
  • "Synthesis of unsymmetrically substituted triarylamines via acceptorless dehydrogenative aromatization using a Pd/C and p-toluenesulfonic acid hybrid relay catalyst"
    Takayama, S.; Yatabe, T.; Koizumi, Y.; Jin, X.; Nozaki, K.; Mizuno, N.; Yamaguchi, K.
    Chem. Sci., 2020, 11, 4074–4084
  • "Selective Synthesis of Primary Anilines from NH3 and Cyclohexanones by Utilizing Preferential Adsorption of Styrene on the Pd Nanoparticle Surface"
    Koizumi, Y.; Jin, X.; Yatabe, T.; Miyazaki, R.; Hasegawa, J.; Nozaki, K.; Mizuno, M.; Yamaguchi, K.
    Angew. Chem. Int. Ed., 2019, 58, 10893-10897
  • "Methyl‐Selective α‐Oxygenation of Tertiary Amines to Formamides by Employing Copper/Moderately Hindered Nitroxyl Radical (DMN‐AZADO or 1‐Me‐AZADO)"
    Nakai, S.; Yatabe, T.; Suzuki, K.; Sasano, Y.; Iwabuchi, Y.; Hasegawa, J.; Mizuno, N.; Yamaguchi, K.
    Angew. Chem. Int. Ed., 2019, 58, 16651-16659
  • "CuCl/TMEDA/nor-AZADO-catalyzed aerobic oxidative acylation of amides with alcohols to produce imides"
    Kataoka, K.; Wachi, K.; *Jin, X.; Suzuki, K.; Sasano, Y.; Iwabuchi, Y.; Hasegawa, J.; Mizuno N.; *Yamaguchi, K.
    Chem. Sci., 2018, 9, 4756-4768
  • "Selective Dehydrogenative Mono- or Diborylation of Styrenes by Supported Copper Catalysts "
    Yoshii, D.; *Jin, X.; Mizuno, N.; *Yamaguchi, K.
    ACS Catal., 2019, 9, 3011-3016
  • "Heterogeneously Palladium-catalyzed Acceptorless Dehydrogenative Aromatization of Cyclic Amines"
    Oyama, T.; Yatabe, T.; Jin, X.; Mizuno, N.; *Yamaguchi, K.
    Chem. Lett., 2019, 48, 517-520
  • "Transition-Metal-Free Catalytic Formal Hydroacylation of Terminal Alkynes"
    Yatabe, T.; Mizuno, N.; *Yamaguchi, K.
    ACS Catal., 2018, 8, 11564-11569
  • "CuCl/TMEDA/nor-AZADO-catalyzed aerobic oxidative acylation of amides with alcohols to produce imides"
    Kataoka, K.; Wachi, K., *Jin, X.; Suzuki, K.; Sasano, Y.; Iwabuchi, Y.; Hasegawa, J.; Mizuno, N.; *Yamaguchi, K.
    Chem. Sci., 2018, 9, 4756-4768
  • "Unusual Olefinic C-H Functionalization of Simple Chalcones Toward Aurones Enabled by the Rational Design of a Function-Integrated Heterogeneous Catalyst"
    Yatabe, T.; Jin, X.; Mizuno, N.; *Yamaguchi, K.
    ACS Catal., 2018, 8, 4969-4978
  • "Aerobic Oxygenation of Alkylarenes over Ultrafine Transition-Metal-Containing Manganese-Based Oxides"
    Nakai, S.; Uematsu, T.; Ogasawara, Y.; Suzuki, K.; *Yamaguchi, K.; *Mizuno, N.
    ChemCatChem, 2018, 10, 1096-1106
  • "Selective Synthesis of Primary Anilines from Cyclohexanone Oximes by the Concerted Catalysis of a Mg-Al Layered Double Hydroxide Supported Pd Catalyst"
    Jin, X.; Koizumi, Y.; Yamaguchi, K.; Nozaki, K.; Mizuno, N.
    J. Am. Chem. Soc., 2017, 139, 13821-13829
  • "Formal arylation of NH3 to produce diphenylamines over supported Pd catalysts"
    Koizumi, Y.; Taniguchi, K.; Jin, X.; Yamaguchi, K.; Nozaki, K.; Mizuno, N.
    Chem. Commun., 2017, 53, 10827-10830
  • "Platinum-supporting hollandite-type vanadium-chromium mixed oxides as efficient heterogeneous catalysts for deoxygenation of sulfoxides under atmospheric H2 pressure"
    Uematsu, T.; Ogasawara, Y.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    Catal. Sci. Technol., 2017, 7, 1912-1920
  • "Versatile routes for synthesis of diarylamines through acceptorless dehydrogenative aromatization catalysis over supported gold–palladium bimetallic nanoparticles"
    Taniguchi, K.; Jin, X.; Yamaguchi, K.; Nozaki,K.; Mizuno, N.
    Chem. Sci., 2017, 8, 2131-2142
  • "Ni–Mg–Al layered triple hydroxide-supported Pd catalyst for heterogeneous acceptorless dehydrogenative aromatization"
    Jin, X.; Taniguchi, K.; Yamaguchi, K.; Nozaki, K.; Mizuno, N.
    Chem. Commun., 2017, 53, 5267–5270.
  • "Gold nanoparticles on OMS-2 for heterogeneously catalyzed aerobic oxidative α, β-dehydrogenation of b-heteroatom-substituted ketones"
    Yoshii, D.; Jin, X.; Yatabe, T.; Hasegawa, J.; Yamaguchi, K.; Mizuno, N.
    Chem. Comm., 2016, 52, 14314-14317
  • "A Ni-Mg-Al layered triple hydroxide-supported Pd catalyst for heterogeneous acceptorless dehydrogenative aromatization"
    Jin, X.; Taniguchi, K.; Yamaguchi, K.; Nozaki, K.; Mizuno, N.
    Chem. Commun., 2017, 53, 5267 - 5270
  • "“Release and catch” catalysis by tungstate species for the oxidative cleavage of olefins"
    Yoshimura, Y.; Ogasawara, Y.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    Catal. Sci. Technol., 2017, 7, 1662-1670
  • "Phosphovanadomolybdic acid catalyzed direct C–H trifluoromethylation of (hetero)arenes using NaSO2CF3 as the CF3 source and O2 as the terminal oxidant"
    Li, C.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    New J. Chem., 2017, 41, 1417-1420
  • "Versatile routes for synthesis of diarylamines through acceptorless dehydrogenative aromatization catalysis over supported gold–palladium bimetallic nanoparticles"
    Taniguchi, K.; Jin, X.; Yamaguchi, K.; Nozaki, K.; Mizuno, N.
    Chem. Sci., 2017, 8, 2131-2142
  • "Gold nanoparticles on OMS-2 for heterogeneously catalyzed aerobic oxidative α,β-dehydrogenation of β-heteroatom-substituted ketones"
    Yoshii, D.; Jin, X.; Yatabe, T.; Hasegawa, J.; Yamaguchi, K.; Mizuno, N.
    Chem. Commun., 2016, 52, 14314-14317
  • "Au-Pd alloy nanoparticles supported on layered double hydroxide for heterogeneously catalyzed aerobic oxidative dehydrogenation of cyclohexanols and cyclohexanones to phenols"
    Jin, X.; Taniguchi, K.; Yamaguchi, K.; Mizuno, N.
    Chem. Sci., 2016, 7 , 5371-5383
  • "Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides"
    Jin, X.; Kataoka, K.; Yatabe, T.; Yamaguchi, K.; Mizuno, N.
    Angew. Chem. Int. Ed., 2016, 55, 7212-7217
  • "Phosphovanadomolybdic acids catalyzed desulfurization-oxygenation of secondary and tertiary thioamides into amides using molecular oxygen as the terminal oxidant"
    Xu, N.; Jin, X.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    New. J. Chem., 2016, 40 , 4865-4869
  • "Rational Low-Temperature Synthesis of Ultrasmall Nanocrystalline Manganese Binary Oxide Catalysts under Controlled Metal Cation Hydration in Organic Media"
    Miyamoto, Y.; Kuroda, Y.; Uematsu, T.; Oshikawa, H.; Shibata, N.; Ikuhara, Y.; Suzuki, K.; Hibino, M. ; Yamaguchi, K.; Mizuno, N.
    ChemNanoMat, 2016, 2, 297-306
  • "Facile access to N-substituted anilines via dehydrogenative aromatization catalysis over supported gold-palladium bimetallic nanoparticles"
    Taniguchi, K.; Jin, X.; Yamaguchi, K.; Mizuno, N.
    Catal. Sci. Technol., 2016, 6, 3929-3937
  • "Synthesis and oxidation catalysis of a Ti-substituted phosphotungstate, and identification of the active oxygen species"
    Takahashi, E.; Kamata, K.; Kikukawa, Y.; Sato, S.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    Catal. Sci. Technol., 2015, 5, 4778-4789
  • "Synthesis of N-Acylsulfenamides through Aerobic Cross Dehydrogenative Coupling of Thiols and Amides by Supported Copper Hydroxide Catalyst"
    Sakagami, K.; Jin, X.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    Chem. Lett., 2016, 45, 173-175
  • "Molybdenum-doped α-MnO2 as an efficient reusable heterogeneous catalyst for aerobic sulfide oxygenation"
    Uematsu, T.; Miyamoto, Y.; Ogasawara, Y.; Suzuki, K.; Yamaguchi, K.; Mizuno, N.
    Catal. Sci. Technol., 2016, 6, 222-233
  • "Synthesis of ultrasmall Li-Mn spinel oxides exhibiting unusual ion exchange, electrochemical, and catalytic properties"
    Miyamoto, Y.; Kuroda, Y.; Uematsu, T.; Oshikawa, H.; Shibata, N.; Ikuhara, Y.; Suzuki, K.; Hibino, M.; Yamaguchi, K.; Mizuno, N.
    Sci. Rep., 2015, 5, 15011
  • "Supported gold-palladium alloy nanoparticles catalyzed tandem oxidation routes to N-substituted anilines from non-aromatic compounds"
    Taniguchi, K.; Jin, X.; Yamaguchi, K.; Mizuno, N.
    Chem. Commun., 2015, 51, 14969-14972
  • "Gold Nanoparticles Supported on a Layered Double Hydroxide as Efficient Catalysts for the One-Pot Synthesis of Flavones"
    Yatabe, T.; Jin, X.; Yamaguchi, K.; Mizuno, N.
    Angew. Chem. Int. Ed., 2015, 54, 13302-13306

国際会議

  • 第4回精密制御反応場国際シンポジウム
    "Hybrid relay catalysis using Pd/C and p-toluenesulfonic acid for synthesizing unsymmetrically substituted triarylamines via acceptorless dehydrogenative aromatization", Poster Presentation
    Takayama, S.; Koizumi, Y.; Yatabe, T.; Mizuno, N.; Yamaguchi, K.
    2019年12月3日~2019年12月5日, Nara, Japan
  • The 8th Asia Pacific Congress on Catalysis
    "GREEN AMIDE PRODUCTION THROUGH CATALYTIC FORMAL OXYGENATION OF AMINES", Oral Presentation
    Yamaguchi, K.; Yatabe1, T.; Jin, X.; Mizuno, N.
    2019年8月4日~2019年8月7日, Bangkok, Thailand
  • 17th Korea-Japan Symposium on Catalysis
    "Dehydrogenative Mono- or Diborylation of Styrenes by Supported Copper Catalysts", Oral Presentation
    Yoshii, D.; Jin, X.; Mizuno, N.; Yamaguchi, K.
    2019年5月20日~2019年5月22日, Jeju, South Korea
  • 17th Korea-Japan Symposium on Catalysis
    "Dehydrogenative Aromatization to Produce Arylamines over Supported Palladium Catalysts", Oral Presentation
    Yamaguchi, K.; Koizumi, Y.; Jin, X.; Mizuno, N.
    2019年5月20日~2019年5月22日, Jeju, South Korea

受賞

  • 「紫綬褒章」
    受賞者:水野哲孝
    贈呈元:内閣府
    受賞日:2016年11月3日

媒体掲載

  • Chem. Sci., カバーピクチャ
    「Synthesis of unsymmetrically substituted triarylamines via acceptorless dehydrogenative aromatization using a Pd/C and p-toluenesulfonic acid hybrid relay catalyst」
    Takayama, S.; Yatabe, T.; Koizumi, Y.; Jin, X.; Nozaki, K.; Mizuno, N.; Yamaguchi, K. , 2020年4月
    PDF File
  • J. Am. Chem. Soc., カバーピクチャ
    「Selective Synthesis of Primary Anilines from Cyclohexanone Oximes by the Concerted Catalysis of a Mg-Al Layered Double Hydroxide Supported Pd Catalyst」
    Jin, X.; Koizumi, Y.; Yamaguchi, K.; Nozaki, K.; Mizuno, N. , 2017年10月4日
    PDF File
  • Chem. Commun., カバーピクチャ
    「A Ni-Mg-Al layered triple hydroxide-supported Pd catalyst for heterogeneous acceptorless dehydrogenative aromatization」
    Jin, X.; Taniguchi, K.; Yamaguchi, K.; Nozaki, K.; Mizuno, N., 2017年5月
    PDF File
  • Catal. Sci. Technol., カバーピクチャ
    「“Release and catch” catalysis by tungstate species for the oxidative cleavage of olefins」
    Yoshimura, Y.; Ogasawara, Y.; Suzuki, K.; Yamaguchi, K.; Mizuno, N., 2017年4月
    PDF File
  • Synfacts, 雑誌記事
    「Gold-Catalyzed Aerobic Oxidative α,β-Dehydrogenation of Ketones」
    Yoshii, D.; Jin. X.; Yatabe, T.; Hasegawa, J.; Yamaguchi, K.; Mizuno, N., 2017年3月
    PDF File
  • Synfacts, 雑誌記事
    「Au-Pd alloy nanoparticles supported on layered double hydroxide for heterogeneously catalyzed aerobic oxidative dehydrogenation of cyclohexanols and cyclohexanones to phenols」
    Jin, X., Taniguchi, K.; Yamaguchi, K.; Mizuno, N., 2016年10月23日
    PDF File
  • Synfacts, 雑誌記事
    「Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides」
    Jin, X.; Kataoka, K.; Yatabe, T.; Yamaguchi, K.; Mizuno, N., 2016年9月6日
    PDF File
  • Synfacts, 雑誌記事
    「Synthesis of N-Acylsulfenamides through Aerobic Cross Dehydrogenative Coupling of Thiols and Amides by Supported Copper Hydroxide Catalyst」
    Sakagami, K.; Jin, X.; Suzuki, K.; Yamaguchi, K.; Mizuno, N., 2016年6月23日
  • New J. Chem., カバーピクチャ
    「Phosphovanadomolybdic acids catalyzed desulfurization-oxygenation of secondary and tertiary thioamides into amides using molecular oxygen as the terminal oxidant」
    Xu, N.; Jin, X.; Suzuki, K.; Yamaguchi, K.; Mizuno, N., 2016年5月
    PDF File
  • ChemNanoMat, カバーピクチャ
    「Rational Low-Temperature Synthesis of Ultrasmall Nanocrystalline Manganese Binary Oxide Catalysts under Controlled Metal Cation Hydration in Organic Media」
    Miyamoto, Y.; Kuroda, Y.; Uematsu, T.; Oshikawa, H.; Shibata, N.; Ikuhara, Y.; Suzuki, K.; Hibino, M.; Yamaguchi, K.; Mizuno, N., 2016年3月29日
    PDF File
  • Synfacts, 雑誌記事
    「Gold Nanoparticles Supported on a Layered Double Hydroxide as Efficient Catalysts for the One-Pot Synthesis of Flavones」
    Yatabe, T.; Jin, X.; Yamaguchi, K.; Mizuno, N., 2016年1月27日
    PDF File
  • Synfacts, 雑誌記事
    「Supported gold-palladium alloy nanoparticles catalyzed tandem oxidation routes to N-substituted anilines from non-aromatic compounds」
    Taniguchi, K.; Jin, X.; Yamaguchi, K.; Mizuno, N. , 2016年1月13日
    PDF File
  • Chem. Commun., カバーピクチャ
    「Supported gold-palladium alloy nanoparticles catalyzed tandem oxidation routes to N-substituted anilines from non-aromatic compounds」
    Taniguchi, K.; Jin, X.; Yamaguchi, K.; Mizuno, N., 2015年8月19日
    PDF File